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001- Milk
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 Sean Penn (in an Oscar-winning role) stars in this fact-based drama about Harvey Milk, the openly gay activist and San Francisco politician who was murdered along with Mayor George Moscone (Victor Garber) by disgruntled city supervisor Dan White (Josh Brolin) in 1978. Emile Hirsch, James Franco and Diego Luna co-star in director Gus Van Sant's compelling biopic, which also earned Oscar nods for Best Picture and Best Supporting Actor (Brolin).
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002- Brokeback Mountain
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 While working together near Wyoming's Brokeback Mountain in 1963, sheepherders Jack Twist (Jake Gyllenhaal) and Ennis Del Mar (Heath Ledger) begin an increasingly passionate affair. But keeping their relationship a secret from their wives (Anne Hathaway and Michelle Williams) proves agonizing and all-consuming. Ang Lee directs this Oscar-winning drama based on a short story by Pulitzer Prize winner E. Annie Proulx.
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003- Transamerica
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 Bree (Felicity Huffman) gets the shock of her life a week before her final sex change surgery when she discovers a son she didn't know she had. After bailing him out of jail, the two set out on a cross-country journey riddled with road bumps. Huffman won numerous awards (and an Oscar nomination) for her role as a man longing to be a woman. Elizabeth Pena, Burt Young, Kevin Zegers and Graham Greene co-star.
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004- The Hours
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 This gripping drama follows the parallel lives of three 20th-century women: the incomparable Virginia Woolf (Nicole Kidman), an unsatisfied 1950s housewife (Julianne Moore), and a modern-day book editor (Meryl Streep) who's losing her former lover to AIDS. Kidman collected a Best Actress Oscar for her role in director Stephen Daldry's adaptation of Michael Cunningham's Pulitzer Prize-winning novel.
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005- Kinsey
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 Liam Neeson turns in a fascinating portrayal of Dr. Alfred Kinsey, who interviewed thousands of people about their sex lives and released his findings in a groundbreaking 1948 book known popularly as "The Kinsey Report." Kinsey's Sexual Behavior in the Human Male (and a subsequent study of females) caused ripples in the scientific community and paved the way for further inquiry into the subject. Laura Linney and Peter Sarsgaard co-star.
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006- Shortbus
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 Director John Cameron Mitchell (Hedwig and the Angry Inch) delivers an unbridled look at the New York City underground, focusing on a group of hipsters who frequent a downtown club renowned for its lascivious ways. Through graphic polymorphous sexual couplings -- and using an ensemble cast composed largely of first-time actors -- the film chronicles each character's erotic journey of self-discovery in a raw and riveting fashion.
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007- A Single Man
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 This stream-of-consciousness, 1960s-era drama centers on a day in the life of George Falconer (Colin Firth, in an Oscar-nominated role), an English-born, Los Angeles college professor reeling from the recent death of his lover of 16 years. Fashion designer Tom Ford makes his directoral debut with this luminous film, which is based on Christopher Isherwood's novel. Julianne Moore, Matthew Goode, Ginnifer Goodwin, Lee Pace and Nicholas Hoult co-star.
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008- Boys Don't Cry
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 When Teena Brandon (Hilary Swank) moves to a small Nebraska town in search of a new life, she takes the name Brandon Teena, passes herself off as a boy, begins dating a beautiful girl (Chloe Sevigny) and makes friends among the town's redneck men ... until the truth is revealed. Swank's Oscar-winning portrayal of this real-life character illuminates one woman's voyage of self-discovery -- and the tragic events that cut it short.
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009- Imagine Me & You
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 In this unconventional romantic comedy that gives new meaning to the term "cold feet," bride-to-be Rachel (Piper Perabo) is love-struck -- not with her groom, but rather with another woman who's a guest at their wedding. As she's marching down the aisle with her longtime sweetheart, Heck (Matthew Goode), Rachel is immediately bewitched by a beautiful guest (Lena Headey). But following her heart's true desire is hardly an easy proposition.
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010- Gia
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 A young Angelina Jolie is mesmerizing in her breakout role as supermodel Gia Carangi, a cover girl who lived fast and died at age 26 from the ravages of AIDS, in this fact-based HBO biopic that won an Emmy and two Golden Globes. The film follows Gia from busing tables at her father's diner to the glamorous world of high-fashion photography -- and finally to her downward spiral into drugs and toxic relationships. Faye Dunaway co-stars.
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011- The History Boys
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 Nicholas Hytner, Richard Griffiths and Frances de la Tour reprise their Tony-winning roles in this engaging film version of Alan Bennett's play, chronicling a rowdy group of boys on their way to higher education. On a quest to attend either Oxford or Cambridge, the teens grapple with the intricacies of university entrance exams and admissions, ultimately learning as much about the education system as they do about academics.
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012- Angels in America
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 Tony Kushner's groundbreaking, Pulitzer Prize-winning Broadway play about love, loss and loneliness -- the basis for this six-hour HBO miniseries -- took more than 10 years to make it to the small screen. Starring Al Pacino (as real-life legal counsel Roy Cohn) and Meryl Streep, the drama examines the first few years of the AIDS epidemic in the mid-1980s, set against the moral absolutism and unresponsive backdrop of the Reagan Administration.
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013- Iris
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 Iris Murdoch (Judi Dench and Kate Winslet, in Oscar-nominated roles) was l'enfant terrible of the literary world in early 1950s Britain -- a live wire who thumbed her nose at conformity via a voracious and scandalous sexual appetite. In this snippet of her life, an aging Murdoch (Dench) faces the onset of Alzheimer's disease and the loss of memories about her younger self (Winslet). Jim Broadbent won the Oscar for his portrayal of her husband.
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014- Gray Matters
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 Sam (Thomas Cavanagh) and Gray (Heather Graham) are a devoted brother and sister who share a dwelling and a love of many things -- ballroom dancing, 1940s movie musicals and, much to their surprise, strong feelings for an attractive woman (Bridget Moynahan). But Gray, who's historically heterosexual, is confused by her strange new feelings. Sibling rivalry, love and destiny go topsy-turvy in first-time writer-director Sue Kramer's romantic romp.
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015- A Home at the End of the World
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 Boyhood pals Bobby (Colin Farrell) and Jonathan (Dallas Roberts) both love the same woman (Robin Wright Penn), but in different ways. (For one thing, Jonathan is gay). Yet, undaunted, they all try to make a life together -- and even have a baby -- in 1980s New York. Pulitzer Prize-winning author Michael Cunningham's novel gets deft treatment in this story about a troika of close friends who enter into an unconventional living arrangement.
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016- Hedwig and the Angry Inch
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 After a botched sex-change operation, East German glam rocker Hansel (John Cameron Mitchell) becomes Hedwig and travels across the United States with a stage show, following her ex-boyfriend (and former band mate) and telling her life story. Hedwig's offbeat show slays audiences -- but in diners not clubs. Mitchell also wrote and directed the comedy, which won at the Sundance Film Festival and was nominated for several Independent Spirit Awards.
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017- Saving Face
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 Dutiful daughter Wil (Michelle Krusiec) sidesteps her mother's (Joan Chen) attempts to marry her off in Alice Wu's romantic comedy. At 28, Wil's the old maid of her traditional Chinese family, so there's no way she can tell them about her budding lesbian romance with Vivian (Lynn Chen). But her widowed mom has her own problems, as she learns she's pregnant at 48. Kicked out by her disapproving father, she seeks refuge at Wil's place.
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018- Before Night Falls
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 Spanning several decades, this powerful biopic offers a glimpse into the life of famed Cuban poet and novelist Reinaldo Arenas (Javier Bardem), an artist who was vilified for his homosexuality in Fidel Castro's Cuba. Although Arenas finds success as a writer, he must eventually emigrate to New York City to enjoy unfettered creative freedom. Johnny Depp co-stars in two different roles as a transvestite inmate and as a warden.
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019- Fried Green Tomatoes
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 In this adaptation of Fanny Flagg's novel, flashbacks reveal the remarkable and mysterious story of soul mates Idgie (Mary Stuart Masterson) and Ruth Jamison (Mary-Louise Parker), whose antics cause an uproar in their rural Southern town during the 1920s. Feisty Ninny Threadgoode (Jessica Tandy) tells the tale to a repressed Alabama housewife (Kathy Bates), who becomes obsessed with Idgie and Ruth, and ultimately finds inspiration in their story.
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020- The L Word: Season 1
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 Follow all the thrilling hook-ups and painful break-ups of a close-knit group of lesbians whose members include Bette (Jennifer Beals), Dana (Erin Daniels), Jenny (Mia Kirshner), Marina (Karina Lombard), Alice (Leisha Hailey), Tina (Laurel Holloman), Shane (Katherine Moennig) and Kit (Pam Grier), all who are proud to live life out of the closet. It's grrrl power all the way in the first season of this controversial Showtime series.
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021- Philadelphia
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 Philadelphia attorney Andrew Beckett (Tom Hanks, in an Oscar-winning role) launches a wrongful termination suit against the hand that feeds him when his law firm finds out about his HIV-positive status -- and his homosexuality -- and fires him. Denzel Washington co-stars as a homophobic lawyer who reluctantly agrees to take Andy's case in this Jonathan Demme-directed film, the first major-studio picture to tackle the topic of AIDS.
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022- The Opposite of Sex
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 When self-involved, reckless and over-the-top Dedee Truitt (Christina Ricci), a 16-year-old "actress," moves in with her brother, Bill (Martin Donovan), and his lover, Matt (Ivan Sergei), she quickly seduces her way into a gender-bending love triangle. Don Roos (Happy Endings) writes and directs this unpredictable dramedy with witty, original narration; Johnny Galecki, Lisa Kudrow, Lyle Lovett and William Lee Scott co-star.
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023- But I'm a Cheerleader
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 In this hilarious satire, Megan Bloomfield (Natasha Lyonne) lives a "normal" teen life as a cheerleader dating the captain of the football team. But her parents and friends suspect Megan is gay because of "clues," such as her distaste for kissing her boyfriend. Shipped off to True Directions -- a camp designed to shove her back in the closet -- Bloomfield meets tomboy Graham Eaton (Clea DuVall), who helps her recognize her sexual orientation.
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024- The Adventures of Priscilla, Queen of the Desert
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 Invited to perform at a casino in remote Alice Springs, Australia, drag queens Mitzi (Hugo Weaving) and Felicia (Guy Pearce) and transsexual Bernadette (Terence Stamp) hit the road in a broken-down lavender bus named Priscilla in this campy comedy classic. Along the way, the friends change into their most outrageous costumes and lip-synch disco tunes -- including plenty of ABBA -- for the outback's befuddled locals.
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025- Tipping the Velvet
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 An unusual love story told in three episodes charts the course of Nan (Rachael Stirling), an ingénue who discovers a sexually charged world of male impersonators, actors and affluent women looking for female companionship in the usually controlled and corseted 1890s. She eventually takes up with a comely cross-dresser (Keeley Hawes) but soon learns she can only depend on herself. John Bowe, Jodhi May, Anna Chancellor and Hugh Bonneville co-star.
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